A 3rd efficient weapon was added to America’s arsenal in opposition to the coronavirus on Saturday when the Meals and Drug Administration granted emergency use authorization for a vaccine developed by Johnson & Johnson.
The corporate stated it could begin transport thousands and thousands of doses early this week, and would offer the USA with 100 million doses by the tip of June. Along with 600 million doses of the nation’s first two licensed vaccines, made by Pfizer-BioNTech and Moderna, which might be attributable to be delivered over the following 4 months, that should be sufficient to cowl each American grownup who needs to be vaccinated.
The brand new vaccine differs markedly from the 2 already in use in the USA. Right here is how they evaluate.
One shot as a substitute of two
The Johnson & Johnson vaccine is run in a single shot, whereas the Pfizer-BioNTech and Moderna vaccines are given in two pictures a number of weeks aside.
The best way it really works
The Johnson & Johnson vaccine makes use of a distinct methodology to prime the physique to combat off Covid-19: a viral vector known as Ad26. Viral vectors are widespread viruses which were genetically altered in order that they don’t trigger sickness however can nonetheless trigger the immune system to construct up its defenses. The Pfizer-BioNTech and Moderna vaccines use messenger RNA to do this.
How properly it really works
The Johnson & Johnson vaccine is rated as extremely efficient at stopping critical sickness and loss of life, because the Pfizer-BioNTech and Moderna vaccines are. It’s also very efficient at stopping milder sickness, although a bit much less so than these two. It seems to do properly in opposition to the extremely contagious B.1.351 variant, first recognized in South Africa, that has given a minimum of one different vaccine candidate hassle.
Storage and dealing with
The Johnson & Johnson vaccine doesn’t need to be saved at extraordinarily low temperatures just like the Pfizer-BioNTech vaccine. It could actually safely be stored in an atypical fridge for 3 months, for much longer than the Moderna vaccine, which spoils after a month if not stored frozen.
The Johnson & Johnson vaccine seems to be much less inclined than the Pfizer-BioNTech and Moderna vaccines to set off the sorts of unwanted side effects that require monitoring after the injection, which can make it extra appropriate to be used at drive-through vaccination websites. There have been studies that unwanted side effects are usually felt extra strongly after second doses, which the Johnson & Johnson vaccine doesn’t require.